Physical Therapy for Hypermobility & Connective Tissue Disorders

Joint hypermobility can affect much more than flexibility. At Tailor-Made Physiotherapy, we provide individualized, one-on-one care to help improve joint stability, reduce pain, build strength, and restore confidence in movement.

Understanding Hypermobility

Joint hypermobility means that one or more joints move beyond the typical range of motion. While many people with hypermobility never develop symptoms, others may experience joint pain, recurrent injuries, instability, fatigue, or difficulty tolerating physical activity. Conditions such as Hypermobility Spectrum Disorder (HSD) and Ehlers-Danlos syndrome (EDS) often require an individualized approach that focuses on improving movement quality rather than simply increasing flexibility.

Common Symptoms

Musculoskeletal Symptoms

  • Chronic joint and limb pain — the most common complaint, often early on, becoming constant and generalized locations with age

  • Recurrent joint subluxations and dislocations

  • Soft-tissue rheumatism: tendinitis, bursitis, enthesopathies, and nerve entrapment syndromes [1]

  • Delayed motor development in children [2]

  • Muscle atrophy, cramps, and muscle pains 

Skin and Connective Tissue

  • Soft, velvety, flexible skin

  • Easy bruising

  • Atrophic or widened, thin, scarring, particularly in classical EDS [3]

  • Stretch marks that start out red or purple and fade white or blue 

Autonomic Dysfunction (Dysautonomia)

The most common autonomic profile is postural orthostatic tachycardia syndrome (POTS), present in approximately 20–58% of patients [4].

Symptoms include:

  • Orthostatic intolerance, dizziness, lightheadedness, presyncope/syncope

  • Palpitations, exercise intolerance

  • Dependent acrocyanosis, impaired thermoregulation [5]

Gastrointestinal Symptoms

Over 60% of hEDS/HSD patients report at least one chronic GI symptom [6]. 

Common manifestations include:

  • Gastroesophageal reflux disease (41%), heartburn (35%) [6]

  • Functional dyspepsia, early satiety, gastroparesis [7]

  • Abdominal pain, bloating [8]

  • Irritable bowel syndrome, constipation , diarrhea [8]

  • Functional dysphagia [6]

Neurological and Neuropsychiatric

  • Chronicfatigue — the most common extraintestinal comorbidity [6]

  • Migraine headaches [6]

  • Small fiber neuropathy with earlier onset and more severe autonomic involvement compared to idiopathic SFN [9]

  • Chiari I malformation, craniocervical instability, tethered cord [7]

  • Impaired memory and concentration [6]

  • Anxiety disorders, depression, and attention-deficit/hyperactivity disorder [7]

Cardiovascular

  • Mitral valve prolapse and/or aortic root dilation [7]

  • Dysrhythmias [10]

  • Arterial aneurysm/dissection (particularly in vascular EDS) [2]

Immune and Allergic

  • Mast cell activation syndrome (MCAS) — reported in ~25–32% of hEDS patients; the clinical triad of hEDS + POTS + MCAS is present in approximately 25% of affected women [4].

  • Food allergies, atopic features, urticaria, flushing [10]

Urogenital and Pelvic

  • Pelvic organ prolapse, urinary incontinence [7]

  • Dysmenorrhea, menorrhagia [7]

  • Interstitial cystitis, bladder dysfunction [7]

How Physical Therapy Can Help

Treatment is designed around your specific symptoms, goals, and functional needs rather than a standardized protocol.

Treatment may include:

  • Joint stabilization exercises

  • Progressive strengthening

  • Manual therapy when appropriate

  • Movement retraining

  • Balance and proprioceptive training

  • Activity modification

  • Pain management strategies

  • Education for long-term self-management

Is Physical Therapy Right for You?

✔ You experience frequent joint pain or instability.

✔ You've had repeated sprains or dislocations.

✔ Exercise often increases your symptoms instead of improving them.

✔ You've been diagnosed with HSD or Ehlers-Danlos syndrome.

✔ You have persistent pain despite previous treatment.

✔ You want to return to normal daily activities and physical activities with greater confidence.

Frequently Asked Questions